Reference

According to Anderson et al., the human plasma proteome ensures nonredundancy by merging four different views of the human plasma proteome, based on different methodologies, into a single nonredundant list of 1175 distinct gene products. This approach helps to confirm the presence of interesting candidate marker proteins in plasma and serum without duplication. The strategy of combining various methodologies allows for a comprehensive and non-overlapping compilation of proteins, ensuring that each entry in the list is unique and contributes to a more accurate understanding of the human plasma proteome. This nonredundant list is crucial for biomarker discovery and understanding the complexity of the human plasma proteome. For more detailed information, you can refer to the publication on ResearchGate. Here is an image depicting the complexity of the human plasma proteome: .