Luke Cage is one of the key members of "The Defenders," a Netflix miniseries that brings together characters from various Marvel series. Luke Cage, along with Daredevil, Jessica Jones, and Iron Fist, teams up to combat a common enemy in New York City. This collaboration is rooted in their shared universe on Netflix, where each character has their own standalone series but eventually comes together as a team in "The Defenders" to tackle a larger threat.
Luke Cage's storyline intersects with Jessica Jones' in particular, as they have a complex relationship that is explored in their respective series and developed further in "The Defenders."
For more details, you can check out this article on Collider for an in-depth explanation.