Studies have investigated various addictive drugs to understand their effects on acetylcholine receptors. Below are some key substances and their interactions:

1. Nicotine: Nicotine, found in tobacco products, is known to bind to nicotinic acetylcholine receptors (nAChRs). This binding enhances neurotransmitter release and is a key factor in its addictive properties.

2. Cocaine: While primarily affecting dopamine transporters, cocaine can also influence acetylcholine receptor activity indirectly, altering overall neural activity and addiction pathways.

3. Ethanol (Alcohol): Alcohol has been shown to modulate both muscarinic and nicotinic acetylcholine receptors, impacting a variety of neural functions and contributing to its addictive potential.

4. Amphetamines: These can interact with the cholinergic system, affecting both muscarinic and nicotinic receptors, which may influence their addictive nature.

5. Opioids: Some research indicates that opioid consumption can alter the functioning of acetylcholine receptors, though these effects are primarily secondary to their interaction with opioid receptors.

Each of these drugs has been the subject of various studies attempting to elucidate the exact mechanisms by which they affect acetylcholine receptors and contribute to their addictive properties.

For more detailed information, you may refer to specific scientific literature available through databases like PubMed or Google Scholar.