Reference

JAK inhibitors are used in various medical treatments due to their ability to modulate the immune system. Here are some common applications:

1. Rheumatoid Arthritis: These inhibitors help reduce inflammation and alleviate symptoms in patients with rheumatoid arthritis by targeting specific pathways in the immune response.

2. Psoriatic Arthritis and Other Inflammatory Arthropathies: JAK inhibitors are effective in treating psoriatic arthritis and other inflammatory joint conditions by reducing excessive inflammation.

3. Myeloproliferative Neoplasms: The drugs are utilized in treating certain blood disorders by modifying the JAK signaling pathway, which is often overactive in these conditions.

4. COVID-19: In some cases, JAK inhibitors have been used to manage severe inflammation in COVID-19 patients.

5. Other Autoimmune Diseases: They are prescribed for various autoimmune disorders where controlling excessive immune activation is crucial.

For more detailed information, you can explore resources like GoodRx and NCBI.