Reference

The method described by Maruyama and Sugano for replacing the mRNA cap structure is known as "oligo-capping". This technique involves two main steps: first, the removal of the cap structure from the mRNA using tobacco acid pyrophosphatase (TAP), and second, the ligation of synthetic oligoribonucleotides to the decapped mRNAs using T4 RNA ligase. This method allows for the replacement of the original cap structure with a synthetic one, which can be useful in various molecular biology applications. The process is outlined in their publication titled "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides" which can be found at this link.