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The "Despicable Me" franchise features a talented lineup of voice actors who bring its beloved characters to life. Some of the most notable voice actors include:

1. Steve Carell - He voices the main character, Gru, known for his distinctive accent and comedic flair, making Gru a memorable and complex character. Source

2. Pierre Coffin - He is not only one of the co-directors of the films but is also known for voicing the Minions, providing them with their unique and entertaining voices. Source

3. Kristen Wiig - She voices Lucy Wilde, Gru's wife, adding her comedic talent to the character.

4. Miranda Cosgrove - She voices Margo, one of Gru's adopted daughters. Source

5. Russell Brand - He provides the voice for Dr. Nefario, Gru's loyal and eccentric scientist assistant. Source

6. Julie Andrews - She voices Gru's mother, adding a touch of class and humor to the character.

These actors, among others, contribute significantly to the charm and appeal of the "Despicable Me" movies, making them a favorite among audiences worldwide.