The PDGFRB gene and the CSF1R gene (164770) encode proteins that belong to the same subfamily of receptor tyrosine kinases (Yarden and Ullrich, 1988). Both genes are located on 5q and are linked physically in a head-to-tail array with less than 500 bp between the polyadenylation signal of the PDGFRB gene and the transcription start point of the

PDGF is the major protein growth factor in human serum and is a markedly heat-stable, cationic protein that consists of two related but nonidentical (36.7% amino-acid sequence identity) polypeptide chains designated A and B (also called PDGF-1 and PDGF-2).1,2 PDGF molecules exist as AA and BB homodimers, as well as an AB heterodimer.7 All of the ligands of the PDGF family exhibit similar

The number of human protein-coding genes is estimated to be around 20,000, ... of the 20,195 structures which belong to the 200 human proteins with the most PDB entries, 4 ,944 and 6 ,928 have mutation(s) or small molecules bound, respectively. ... Membrane proteins represent 20-30% of human proteins. In many earlier reports, it was noted

The PDGFRB gene and the CSF1R gene (164770) encode proteins that belong to the same subfamily of receptor tyrosine kinases (Yarden and Ullrich, 1988). Both genes are located on 5q and are linked physically in a head-to-tail array with less than 500 bp between the polyadenylation signal of the PDGFRB gene and the transcription start point of the

PDGF is the major protein growth factor in human serum and is a markedly heat-stable, cationic protein that consists of two related but nonidentical (36.7% amino-acid sequence identity) polypeptide chains designated A and B (also called PDGF-1 and PDGF-2).1,2 PDGF molecules exist as AA and BB homodimers, as well as an AB heterodimer.7 All of the ligands of the PDGF family exhibit similar

The number of human protein-coding genes is estimated to be around 20,000, ... of the 20,195 structures which belong to the 200 human proteins with the most PDB entries, 4 ,944 and 6 ,928 have mutation(s) or small molecules bound, respectively. ... Membrane proteins represent 20-30% of human proteins. In many earlier reports, it was noted

The PDGFRB gene and the CSF1R gene (164770) encode proteins that belong to the same subfamily of receptor tyrosine kinases (Yarden and Ullrich, 1988). Both genes are located on 5q and are linked physically in a head-to-tail array with less than 500 bp between the polyadenylation signal of the PDGFRB gene and the transcription start point of the

PDGF is the major protein growth factor in human serum and is a markedly heat-stable, cationic protein that consists of two related but nonidentical (36.7% amino-acid sequence identity) polypeptide chains designated A and B (also called PDGF-1 and PDGF-2).1,2 PDGF molecules exist as AA and BB homodimers, as well as an AB heterodimer.7 All of the ligands of the PDGF family exhibit similar

The number of human protein-coding genes is estimated to be around 20,000, ... of the 20,195 structures which belong to the 200 human proteins with the most PDB entries, 4 ,944 and 6 ,928 have mutation(s) or small molecules bound, respectively. ... Membrane proteins represent 20-30% of human proteins. In many earlier reports, it was noted