Annexin A13 shows high expression levels in specific human tissues, particularly in the gastrointestinal tract, bile ducts, gallbladder, renal tubules, and fallopian tubes, as summarized by The Human Protein Atlas [1]. It is also highly expressed in most renal cell carcinoma tissues [2]. Notably, annexin A13 is not expressed in normal epithelial cells but is found at moderate or high levels in tumor cells in 58.4% of colorectal cancer cases [3]. The protein is detected in epithelial cells in the colon and jejunum at the protein level [4]. The expression pattern of annexin A13 is tissue- and cell type-specific, with limited expression in other tissues [5]. Here is an image illustrating the expression of annexin A13 in human colorectal cancer tissues 6.
References: [1] The Human Protein Atlas [2] NCBI [3] NCBI [4] UniProtKB [5] BMC Cancer [6] ResearchGate
How does Annexin A13 contribute to signal transduction pathways?
How is Annexin A13 expression different in humans compared to mice?
Which cellular components are associated with Annexin A13 localization?
What role does Annexin A13 play in cellular growth regulation?
What is the significance of annexin A13 in human intestinal epithelial cell growth?